Published online May 28, 2015. doi: 10.3748/wjg.v21.i20.6304
Peer-review started: March 3, 2015
First decision: March 10, 2015
Revised: March 24, 2015
Accepted: April 28, 2015
Article in press: April 28, 2015
Published online: May 28, 2015
Core tip: Plasma exchange and continuous venous-venous hemofiltration have certain clinical effects in the treatment of hyperlipidemia acute severe pancreatitis, but there is currently no standardized combination therapy. Based on the 2012 Atlanta International Pancreatitis Consensus, we designed a sequential mode of combined application of plasma exchange and continuous venous-venous hemofiltration for the treatment of hyperlipidemia severe acute pancreatitis. This sequential blood purification therapy was found to be effective in the treatment of intensive care unit patients with hyperlipidemic severe acute pancreatitis and improved patient prognosis, and should therefore become the standardized treatment process.