Cholecystectomy is independently associated with nonalcoholic fatty liver disease in an Asian population
Min-Sun Kwak, Donghee Kim, Goh Eun Chung, Won Kim, Yoon Jun Kim, Jung-Hwan Yoon
Min-Sun Kwak, Donghee Kim, Goh Eun Chung, Department of Internal Medicine, Healthcare Research Institute, Healthcare System Gangnam Center, Seoul National University Hospital, Seoul 135-984, South Korea
Won Kim, Department of Internal Medicine, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul 135-984, South Korea
Yoon Jun Kim, Jung-Hwan Yoon, Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul 135-984, South Korea
Author contributions: Kim D contributed to the conception and design of the study; Kwak MS and Kim D contributed to the acquisition, analysis and interpretation of the data and wrote the paper; Chung GE, Kim W, Kim YJ, and Yoon JH contributed to the acquisition of the data and reviewed the paper.
Supported by Seoul National University Hospital Research Fund, No. 04-2014-0660.
Ethics approval: The study was reviewed and approved by the Institutional Review Board of Seoul National University Hospital, No. H1309-019-518.
Informed consent: The need to obtain informed consent from the subjects was waived by the Institutional Review Board of Seoul National University Hospital.
Conflict-of-interest: The authors have no conflicts of interest to declare. The funding organizations played no role in the design and conduct of the study, the collection, analysis, and interpretation of the data, or in the writing, review, and approval of the manuscript.
Data sharing: The technical appendix, statistical code and dataset are available from the corresponding author at messmd@chol.com. No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Donghee Kim, MD, PhD, Department of Internal Medicine, Healthcare Research Institute, Healthcare System Gangnam Center, Seoul National University Hospital, Seoul 135-984, South Korea. messmd@chol.com
Telephone: +82-2-21125574 Fax: +82-2-21125635
Received: December 3, 2014
Peer-review started: December 5, 2014
First decision: January 22, 2015
Revised: February 9, 2015
Accepted: April 3, 2015
Article in press: April 3, 2015
Published online: May 28, 2015
