Retrospective Study
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. May 28, 2015; 21(20): 6280-6286
Published online May 28, 2015. doi: 10.3748/wjg.v21.i20.6280
Significance of the preoperative neutrophil-to-lymphocyte ratio in the prognosis of patients with gastric cancer
Liang Yu, Cheng-Yu Lv, Ai-Hua Yuan, Wei Chen, An-Wei Wu
Liang Yu, Cheng-Yu Lv, Ai-Hua Yuan, Wei Chen, An-Wei Wu, Department of General Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, Jiangsu Province, China
Author contributions: Lv CY designed the research; Yu L and Wu AW performed the research; Yuan AH and Che W carried out the data collection and analysis; Yu L drafted the manuscript; Lv CY revised the manuscript critically for important intellectual content.
Supported by Nanjing Science and Technology Project, No. 201106016.
Ethics approval: The study was reviewed and approved by the Nanjing First Hospital, Nanjing Medical University Institutional Review Board.
Informed consent: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest: The authors declare that there is no conflict of interest to disclose.
Data sharing: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Cheng-Yu Lv, Professor, Department of General Surgery, Nanjing First Hospital, Nanjing Medical University, No. 68 Changle Road, Nanjing 210006, Jiangsu Province, China.
Telephone: +86-25-52271070 Fax: +86-25-52271081
Received: November 30, 2014
Peer-review started: November 30, 2014
First decision: January 8, 2015
Revised: February 2, 2015
Accepted: March 18, 2015
Article in press: March 19, 2015
Published online: May 28, 2015
Core Tip

Core tip: This research preliminarily investigated the relationship between the preoperative neutrophil-to-lymphocyte ratio (NLR) and gastric cancer. The results revealed that a high NLR corresponded to poor prognosis of gastric cancer patients. Furthermore, preoperative NLR could be used as a prognostic factor for these patients.