Durazzo M, Belci P, Collo A, Prandi V, Pistone E, Martorana M, Gambino R, Bo S. Gender specific medicine in liver diseases: A point of view. World J Gastroenterol 2014; 20(9): 2127-2135 [PMID: 24605011 DOI: 10.3748/wjg.v20.i9.2127]
Corresponding Author of This Article
Marilena Durazzo, Professor, Department of Medical Science, University of Turin, Corso A.M. Dogliotti 14, 10126 Turin, Italy. marilena.durazzo@unito.it
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Mar 7, 2014; 20(9): 2127-2135 Published online Mar 7, 2014. doi: 10.3748/wjg.v20.i9.2127
Gender specific medicine in liver diseases: A point of view
Marilena Durazzo, Paola Belci, Alessandro Collo, Vanessa Prandi, Erika Pistone, Maria Martorana, Roberto Gambino, Simona Bo
Marilena Durazzo, Paola Belci, Alessandro Collo, Vanessa Prandi, Erika Pistone, Maria Martorana, Roberto Gambino, Simona Bo, Department of Medical Sciences, University of Turin, 10126 Turin, Italy
Author contributions: Durazzo M participated in the conception and design of the review, manuscript writing and revision; Belci P, Collo A, Prandi V, Pistone E, Martorana M, Gambino R and Bo S participated manuscript writing; all authors read and approved the final manuscript.
Correspondence to: Marilena Durazzo, Professor, Department of Medical Science, University of Turin, Corso A.M. Dogliotti 14, 10126 Turin, Italy. marilena.durazzo@unito.it
Telephone: +39-11-6336040 Fax: +39-11-6335401
Received: September 2, 2013 Revised: November 1, 2013 Accepted: December 5, 2013 Published online: March 7, 2014
Core Tip
Core tip: Gender medicine focuses on the patho-physiological, clinical, prevention and treatment differences in diseases that are equally represented in men and women. The concept of “gender” includes not only the sexual characteristics of individuals but also physiological and psychological attributes of men and women. In this review, we critically analyze the literature regarding gender differences for diseases and acquired conditions of the most representative hepatic pathologies: primary biliary cirrhosis, autoimmune hepatitis, primary sclerosing cholangitis, non alcoholic fatty liver disease and alcoholic liver disease, viral chronic hepatitis B and C, and hemochromatosis (the prevalent iron overload disorder in the Caucasian population).
