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World J Gastroenterol. Nov 14, 2014; 20(42): 15860-15866
Published online Nov 14, 2014. doi: 10.3748/wjg.v20.i42.15860
Published online Nov 14, 2014. doi: 10.3748/wjg.v20.i42.15860
Spontaneous and antiviral-induced cutaneous lesions in chronic hepatitis B virus infection
Ioana Grigorescu, Dan Lucian Dumitrascu, 2nd Department of Internal Medicine, University of Medicine and Pharmacy “Iuliu Hatieganu”, 400006 Cluj-Napoca, Romania
Author contributions: Grigorescu I performed the literature research and wrote the paper; Dumitrascu DL designed the paper, participated in the analysis of the data, and contributed to the writing of the manuscript.
Correspondence to: Dan Lucian Dumitrascu, MD, Professor, Head of the 2nd Department Internal Medicine, University of Medicine and Pharmacy “Iuliu Hatieganu”, Clinicilor Street 2-4, 400006 Cluj-Napoca, Romania. ddumitrascu@umfcluj.ro
Telephone: +40-264-593355 Fax: +40-264-596912
Received: October 28, 2013
Revised: March 3, 2014
Accepted: June 13, 2014
Published online: November 14, 2014
Revised: March 3, 2014
Accepted: June 13, 2014
Published online: November 14, 2014
Core Tip
Core tip: Chronic hepatitis B is a common infection with various etiologies, including the involvement of several systems. We investigated the skin lesions of patients with chronic or acute hepatitis B. We also looked for skin lesions related to vaccination and antiviral therapy. Most common lesions in chronic hepatitis B virus infection encountered in a comprehensive literature search are: 41% essential mixed cryoglobulinemia and 15.3% vasculitis; 10.5% (lichen planus-like lesions) respectiveley 7.2% of all lesions included in the review were associated with immunization (lichen planus) and antiviral therapy (lupus-like lesions).