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World J Gastroenterol. Nov 14, 2014; 20(42): 15845-15851
Published online Nov 14, 2014. doi: 10.3748/wjg.v20.i42.15845
Published online Nov 14, 2014. doi: 10.3748/wjg.v20.i42.15845
Randomized controlled trial of sodium phosphate tablets vs polyethylene glycol solution for colonoscopy bowel cleansing
Yoon Suk Jung, Dong Il Park, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul 110-746, South Korea
Chang Kyun Lee, Hyo Jong Kim, Department of Internal Medicine, Kyung Hee University School of Medicine, Seoul 110-746, South Korea
Chang Soo Eun, Dong Soo Han, Department of Internal Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Seoul 110-746, South Korea
Author contributions: Jung YS, Lee CK, Kim HJ, Eun CS, Han DS and Park DI designed research and acquired data; Jung YS, Lee CK, Eun CS and Park DI performed research; Jung YS analyzed data and wrote the paper; Jung YS, Lee CK, Kim HJ, Eun CS, Han DS and Park DI revised the manuscript critically for important intellectual content and approved the version to be submitted.
Correspondence to: Dong Il Park, MD, PhD, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 108, Pyung-Dong, Jongro-Ku, Seoul 110-746, South Korea. diksmc.park@samsung.com
Telephone: +82-2-20012059 Fax: +82-2-20012049
Received: December 15, 2013
Revised: February 22, 2014
Accepted: June 2, 2014
Published online: November 14, 2014
Revised: February 22, 2014
Accepted: June 2, 2014
Published online: November 14, 2014
Core Tip
Core tip: Sodium phosphate (NaP) tablets were equally efficacious as standard 4 L polyethylene glycol (PEG) solution for bowel cleansing for colonoscopy and did not results in greater side effects. Furthermore, patient acceptance and satisfaction of NaP tablets were superior to 4 L PEG solution. NaP tablets in this trial were safe, well-tolerated, and efficient for bowel preparation in the relatively young (age < 60 years) healthy individuals without comorbidity. A more acceptable oral tablet formation might provide a valuable alternative for individuals who are reluctant to undergo colonoscopy because of aversion to the currently available purgatives.