Could JC virus provoke metastasis in colon cancer?

doi:10.3748/wjg.v20.i42.15745

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Nov 14, 2014 (publication date) through Apr 25, 2024

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World Journal of Gastroenterology

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1007-9327

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Case Control Study

World J Gastroenterol. Nov 14, 2014; 20(42): 15745-15749
Published online Nov 14, 2014. doi: 10.3748/wjg.v20.i42.15745

Could JC virus provoke metastasis in colon cancer?

Emanuele Sinagra, Dario Raimondo, Elena Gallo, Mario Stella, Mario Cottone, Ambrogio Orlando, Francesca Rossi, Emanuele Orlando, Marco Messina, Giovanni Tomasello, Attilio Ignazio Lo Monte, Ennio La Rocca, Aroldo Gabriele Rizzo

Emanuele Sinagra, Dario Raimondo, Francesca Rossi, Gastroenterology and Endoscopy Unit, Fondazione Istituto San Raffaele-G Giglio, Contrada Pietra Pollastra Pisciotto, 90015 Cefalù, Italy

Emanuele Sinagra, PhD course in Surgical Biotechnology and Regenerative Medicine, University of Palermo, 90127 Palermo, Italy

Emanuele Sinagra, Giovanni Tomasello, Attilio Ignazio Lo Monte, Euro-Mediterranean Institute of Science and Technology (IEMEST), 90139 Palermo, Italy

Elena Gallo, Mario Stella, Aroldo Gabriele Rizzo, Unit of Pathology, Ospedali Riuniti Villa Sofia - Cervello, University of Palermo, 90136 Palermo, Italy

Mario Cottone, Ambrogio Orlando, Emanuele Orlando, DIBIMIS, Unit of Internal Medicine, Ospedali Riuniti Villa Sofia - Cervello, University of Palermo, 90136 Palermo, Italy

Marco Messina, Oncology Unit, Fondazione Istituto San Raffaele-G Giglio, Contrada Pietra Pollastra Pisciotto, 90015 Cefalù, Italy

Giovanni Tomasello, Attilio Ignazio Lo Monte, Department of Surgical and Oncological Disciplines, School of Medicine, University of Palermo, 90136 Palermo, Italy

Ennio La Rocca, Unità Operativa di Medicina interna e trapiantologia, Ospedale San Raffaele, 20132 Milano, Italy

Author contributions: Sinagra E wrote the paper; Gallo E and Rizzo AG designed the project of the study; Stella M collected the pathological data; Orlando E, Rossi F, Tomasello G and Messina M collected the clinical data; Orlando A, Raimondo D, La Rocca E and Lo Monte AI, Cottone M revised critically the manuscript.

Correspondence to: Emanuele Sinagra, MD, Gastroenterology and Endoscopy Unit, Fondazione Istituto San Raffaele-G Giglio, Contrada Pietra Pollastra Pisciotto, 90015 Cefalù, Italy. emanuelesinagra83@googlemail.com

Telephone: +39-921-920712 Fax: +39-921-920406

Received: November 29, 2013
Revised: May 5, 2014
Accepted: May 19, 2014
Published online: November 14, 2014

Core Tip

Core tip: This is the first case-control study, to our knowledge, assessing, although with a small sample size, the potential metastatic spread of John Cunningham virus associated with colon cancer.