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World J Gastroenterol. Nov 14, 2014; 20(42): 15580-15589
Published online Nov 14, 2014. doi: 10.3748/wjg.v20.i42.15580
Utility of PET/CT in diagnosis, staging, assessment of resectability and metabolic response of pancreatic cancer
Xiao-Yi Wang, Feng Yang, Chen Jin, De-Liang Fu
Xiao-Yi Wang, Feng Yang, Chen Jin, De-Liang Fu, Pancreatic Disease Institute, Department of Pancreatic Surgery, Huashan Hospital, Fudan University, Shanghai 200040, China
Xiao-Yi Wang, Feng Yang, Chen Jin, De-Liang Fu, Department of Surgery, Shanghai Medical College, Fudan University, Shanghai 200032, China
Author contributions: Wang XY contributed to the conception and design of the review, data acquisition, analysis and interpretation, drafting and revising the article, and final approval of the version to be published; Yang F contributed to the conception and design of the review, revising it critically for important intellectual content and the final approval of the version to be published; Jin C and Fu DL contributed to the conception and design of the review and final approval of it.
Supported by The New Outstanding Youth Program of Shanghai Municipal Health Bureau, No. XYQ2013090; the Shanghai Young Physician Training Program, the Zhuo-Xue Project of Fudan University; the Scientific Research Project supported by Huashan Hospital, Fudan University, No. 2013QD21; the National Natural Science Foundation of China, No. 81071884; Research Fund for the Doctoral Program of Higher Education of China, No. 20110071110065
Correspondence to: Feng Yang, MD, Pancreatic Disease Institute, Department of Pancreatic Surgery, Huashan Hospital, Shanghai Medical College, Fudan University, 12 Central Urumqi Road, Shanghai 200040, China. yffudan98@126.com
Telephone: +86-21-52887164 Fax: +86-21-52888277
Received: October 27, 2013
Revised: January 21, 2014
Accepted: March 12, 2014
Published online: November 14, 2014
Core Tip

Core tip: Position emission tomography/computed tomography (PET/CT) is a useful modality in the detection of pancreatic cancer, while its use in staging is limited by the lack of enhanced CT scan and a relatively poor sensitivity in detecting metastatic lymph nodes. It has the advantage in monitoring metabolic response, making it optimal in evaluation of different kinds of treatment and also in detecting suspected recurrence. The correlation between Standardized Uptake Value and prognosis remains controversial. Many efforts have been made to improve the diagnostic efficacy of PET/CT.