Clinical Trials Study
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World J Gastroenterol. Oct 28, 2014; 20(40): 14927-14933
Published online Oct 28, 2014. doi: 10.3748/wjg.v20.i40.14927
Effect of somatostatin in advanced gastric cancer after D2 radical gastrectomy
Wu Song, Jian-Hui Chen, Xin-Hua Zhang, Jian-Bo Xu, Yu-Long He, Shi-Rong Cai, Fang-Hai Han, Chuang-Qi Chen
Wu Song, Jian-Hui Chen, Xin-Hua Zhang, Jian-Bo Xu, Yu-Long He, Shi-Rong Cai, Fang-Hai Han, Chuang-Qi Chen, Gastric Cancer Center, Sun Yat-Sen University, Guangzhou 510080, Guangdong Province, China
Wu Song, Jian-Hui Chen, Xin-Hua Zhang, Jian-Bo Xu, Yu-Long He, Shi-Rong Cai, Fang-Hai Han, Chuang-Qi Chen, Division of Gastrointestinal Surgery, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510080, Guangdong Province, China
Author contributions: Song W and Chen JH contributed equally to this work; Song W, Chen JH and He YL designed research; Song W, Zhang XH, Xu JB, He YL, Cai SR, Han FH and Chen CQ performed research; Chen JH, Zhang XH and Xu JB analyzed data; and Song W and Chen JH wrote the paper.
Supported by Guangdong Province Science and Technology Plan Project, No. 2011B031800240 and No. 2012B031800389; and Guangdong Province Natural Science Fund, No. 52013010015528
Correspondence to: Yu-Long He, MD, Department of Gastrointestinal Surgery, The First Affiliated Hospital of Sun Yat-Sen University, Zhongshan Road No 2, Guangzhou 510080, Guangdong Province, China. ylh@medmail.com.cn
Telephone: +86-20-87755766 Fax: +86-20-87331509
Received: March 27, 2014
Revised: May 15, 2014
Accepted: July 22, 2014
Published online: October 28, 2014
Core Tip

Core tip: To enhance the degree of radical lymph nodes dissection for advanced gastric cancer, vagina vasorum dissection and the resection of extracapsular greater omentum was applied to D2 lymph node dissection. Vagina vasorum dissection was the complete removal of vascular adventitia and fibrous connective tissue as well as nerve tissue around the vascular sheath. But these procedure usually followed by operation-related complications. Hence It is interesting to found out the clinical effect of postoperative somatostatin treatment in the duration and amount of drain followed by gastrectomy and D2 lymphadenectomy with extra capsular epiploon resection.