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World J Gastroenterol. Oct 28, 2014; 20(40): 14921-14926
Published online Oct 28, 2014. doi: 10.3748/wjg.v20.i40.14921
Published online Oct 28, 2014. doi: 10.3748/wjg.v20.i40.14921
Risk factor analysis of perioperative mortality after ruptured bleeding in hepatocellular carcinoma
Hao-Ming Lin, Guo-Lin Li, Jun Min, Department of Hepatobiliary Surgery, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Guangzhou 510120, Guangdong Province, China
Li-Ming Lei, ICU of Cardiac Surgery, Guangdong General Hospital, Guangzhou 510030, Guangdong Province, China
Jie Zhu, Department of Emergency Surgery, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Guangzhou 510120, Guangdong Province, China
Author contributions: Lin HM and Lei LM performed the majority of data collection and analysis, these two authors contributed equally to this work and should be considered co-first authors; Zhu J provided vital analytical tools and was also involved in editing the manuscript; Li GL co-ordinated and provided the collection of some data; Min J designed the study and also provided financial support for this work.
Correspondence to: Jun Min, Professor, Department of Hepatobiliary Surgery, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, No.107 Yanjiang West Road, Guangzhou 510120, Guangdong Province, China. surgeon0001@163.com
Telephone: +86-20-34071165 Fax: +86-20-34071163
Received: March 8, 2014
Revised: August 16, 2014
Accepted: September 18, 2014
Published online: October 28, 2014
Revised: August 16, 2014
Accepted: September 18, 2014
Published online: October 28, 2014
Core Tip
Core tip: The univariate analysis of 60 cases of ruptured bleeding in primary hepatocellular carcinoma revealed that Child-Pugh C level liver function, shock, massive blood transfusion and large tumour volume were risk factors that influenced 30-d mortality. Multivariate analysis showed that shock and massive blood transfusion were independent risk factors that impacted the 30-d mortality of surgical resection. As for the transcatheter arterial embolization (TAE) patients, larger tumour volume was a risk factor towards prognosis. Radical resection and TAE therapy would achieve better results than non-surgical treatment in carefully selected cases of ruptured hepatocellular tumour.