Original Article
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World J Gastroenterol. Oct 28, 2014; 20(40): 14865-14874
Published online Oct 28, 2014. doi: 10.3748/wjg.v20.i40.14865
Wireless esophageal pH capsule for patients with gastroesophageal reflux disease: A multicenter clinical study
Xiao-Jun Yang, Tian Gan, Lei Wang, Zhuan Liao, Xiao-Hong Tao, Wei Shen, Xiao-Yan Zhao
Xiao-Jun Yang, Tian Gan, Lei Wang, Xiao-Yan Zhao, Department of Gastroenterology, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China
Zhuan Liao, Department of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China
Xiao-Hong Tao, Department of Gastroenterology, First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China
Wei Shen, Department of Gastroenterology, Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China
Author contributions: Yang XJ and Gan T wrote the paper and contributed equally to this study; Yang X, Gan T, Wang L, Liao Z, Tao XH, Shen W and Zhao XY performed the research; Yang XJ and Gan T analyzed the data; and Zhao XY designed this research.
Supported by Grants from the Innovation Fund for Technology-Based Firms of the Ministry of Science and Technology of the China, No. 12C26215115999 (in part); Special Fund on Industrial Revitalization and Transformation of the National Development and Reform Commission of the China; and Jinshan Science and Technology Co. Ltd, Chongqing, China
Correspondence to: Xiao-Yan Zhao, Professor, Department of Gastroenterology, Xinqiao Hospital, Third Military Medical University, No. 30 Gaotanyan Street, Shapingba District, Chongqing 400037, China. zhaoxx@medmail.com.cn
Telephone: +86-23-67063969 Fax: +86-23-68774604
Received: December 26, 2013
Revised: May 5, 2014
Accepted: July 22, 2014
Published online: October 28, 2014
Core Tip

Core tip: The new pH capsule (JSPH-1, made by Jinshan Science and Technology Co. Ltd, Chongqing, China), a wireless pH capsule developed in China, was introduced as an alternative method for pH monitoring. Compared with the result recorded synchronously with MMS catheter, that obtained with JSPH-1 pH capsule was of uniformity. Our study suggested that JSPH-1 pH capsule is feasible, safe, well tolerated for monitoring reflux in patients with gastroesophageal reflux disease (GERD), therefore it may serve as an important tool for the diagnosis of GERD.