Managing osteoporosis in ulcerative colitis: Something new?

doi:10.3748/wjg.v20.i39.14087

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Oct 21, 2014 (publication date) through Apr 23, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 21, 2014; 20(39): 14087-14098
Published online Oct 21, 2014. doi: 10.3748/wjg.v20.i39.14087

Managing osteoporosis in ulcerative colitis: Something new?

Luca Petruccio Piodi, Alessandro Poloni, Fabio Massimo Ulivieri

Luca Petruccio Piodi, Fondazione Irccs Ca’ Granda Ospedale Maggiore Policlinico of Milan, 2^nd Gastroenterology Unit, 20122 Milan, Italy

Alessandro Poloni, Scuola di Specializzazione in Radiodiagnostica, Università degli Studi di Milano, Radiology Unit, 20097 San Donato Milanese, Italy

Fabio Massimo Ulivieri, Fondazione Irccs Ca' Granda Ospedale Maggiore Policlinico, Nuclear Medicine, Bone Metabolic Unit, 20122 Milan, Italy

Author contributions: Piodi LP contributed to concept, write and revise the article; Poloni A contributed in acquisition of data and to draft the article; Ulivieri FM contributed to concept, write and revise the article.

Correspondence to: Fabio Massimo Ulivieri, MD, Fondazione Irccs Ca' Granda Ospedale Maggiore Policlinico, Nuclear Medicine, Bone Metabolic Unit, via F.Sforza 35, 20122 Milan, Italy. ulivieri@gmail.com

Telephone: +39-2-55033529 Fax:+39-2-55034382

Received: March 8, 2014
Revised: May 12, 2014
Accepted: June 26, 2014
Published online: October 21, 2014

Core Tip

Core tip: Diagnosis and treatment of osteoporosis in ulcerative colitis are discussed according to the latest evidence. Innovative applications of new programs derived from bone densitometry to evaluate bone quality and to predict fracture risk in patients affected by ulcerative colitis are described. Charts for ten years fracture risk may be utilized to refer patients to bone densitometry and/or to prescribe drugs against osteoporosis. Trabecular bone score and hip structural analysis may be considered to assess bone quality, that could be impaired by malabsorption and chronic inflammatory status. Advices for prevention and treatment of bone damage are given, also considering cost-effectiveness.