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World J Gastroenterol. Oct 7, 2014; 20(37): 13582-13590
Published online Oct 7, 2014. doi: 10.3748/wjg.v20.i37.13582
Published online Oct 7, 2014. doi: 10.3748/wjg.v20.i37.13582
Clinical characteristics and current management of hepatitis B and C in China
Yong-Tao Sun, Department of Infectious Diseases, Tangdu Hospital, Affiliated to the Fourth Military Medical University, Xi’an 710038, Shaanxi Province, China
Yue-Xin Zhang, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, Xinjiang Uygur Autonomous Region, China
Hong Tang, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
Qing Mao, the First Affiliated Hospital of the Third Military Medical University, Chongqing 400039, China
Xiao-Zhong Wang, Traditional Chinese Medicine Hospital of Xinjiang Uygur Administrative Region, Urumqi 830054, Xinjiang Uygur Autonomous Region, China
Ling-Yi Zhang, the Second Affiliated Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China
Hong Chen, the First Affiliated Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China
Ying-Na Zhong, People’s Hospital of Xinjiang Uygur Administrative Region, Urumqi 830054, Xinjiang Uygur Autonomous Region, China
Shu-Mei Lin, the First Affiliated Hospital of Xi'an Jiaotong University, Xi’an 710038, Shaanxi Province, China
Da-Zhi Zhang, the Second Affiliated Hospital of Chongqing Medica University, Chongqing 400039, China
Author contributions: All authors contributed to the acquisition of data, interpretation and analysis of the data, and critical review of the manuscript for important intellectual content; assistance in writing the manuscript was provided by Merck Sharp and Dohme (China) Ltd; all authors read and approved the final manuscript.
Supported by Financial support for this study was provided by Merck Sharp and Dohme (China) Ltd
Correspondence to: Yong-Tao Sun, Department of Infectious Diseases, Tangdu Hospital, Affiliated to the Fourth Military Medical University, No. 569 Xinsi Road, Xi’an 710038, Shaanxi Province, China. yongtaos@hotmail.com
Telephone: +86-29-84777452 Fax: +86-29-83537377
Received: March 24, 2014
Revised: May 16, 2014
Accepted: June 12, 2014
Published online: October 7, 2014
Revised: May 16, 2014
Accepted: June 12, 2014
Published online: October 7, 2014
Core Tip
Core tip: This observational, real-life study has identified some gaps between current clinical practice and guideline recommendations for the treatment of hepatitis B and C infections in China. To achieve better health outcomes, the findings of the study point to various improvements that need to be made to align clinical practice more closely with treatment guidelines, including: (1) routine screening for infections so that patients are diagnosed earlier; (2) more thorough evaluation of hepatitis B virus (HBV)/hepatitis C virus (HCV)-infected patients; and (3) the use of more effective antiviral agents for both anti-HBV and anti-HCV therapy and adjustment of the treatments according to the response.