Review
Copyright ©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 14, 2014; 20(34): 12132-12143
Published online Sep 14, 2014. doi: 10.3748/wjg.v20.i34.12132
Hepatitis C virus infection in the human immunodeficiency virus infected patient
Louise Nygaard Clausen, Lene Fogt Lundbo, Thomas Benfield
Louise Nygaard Clausen, Lene Fogt Lundbo, Thomas Benfield, Department of Infectious Diseases, Hvidovre Hospital, University of Copenhagen, 2650 Hvidovre, Denmark
Lene Fogt Lundbo, Thomas Benfield, Clinical Research Centre, Hvidovre Hospital, University of Copenhagen, 2650 Hvidovre, Denmark
Lene Fogt Lundbo, Thomas Benfield, Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2650 Hvidovre, Denmark
Author contributions: Clausen LN and Lundbo LF performed research and wrote first draft of the paper; Clausen LN, Lundbo LF and Benfield T wrote and revised the final manuscript.
Correspondence to: Louise Nygaard Clausen, MD, PhD, Department of Infectious Diseases, Hvidovre Hospital, University of Copenhagen, Kettegård Allé 30, 2650 Hvidovre, Denmark. louisenygaardclausen@gmail.com
Telephone: +45-38-622108 Fax: +45-38-623797
Received: December 18, 2013
Revised: April 2, 2014
Accepted: June 26, 2014
Published online: September 14, 2014
Core Tip

Core tip: Hepatitis C virus (HCV) infection incidence has increased among men who have sex with men. Additionally, mortality and morbidity from chronic HCV infection has increased and liver-related deaths are now more common than Acquired Immune Deficiency Syndrome-related deaths. Several new direct-acting antiviral agents have been developed or are under development, and therapy strategies change faster than guidelines can be updated. This review focuses on the epidemiology, diagnosis, natural course and treatment of HCV infection in human immunodeficiency virus infected patients.