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World J Gastroenterol. Sep 7, 2014; 20(33): 11916-11920
Published online Sep 7, 2014. doi: 10.3748/wjg.v20.i33.11916
Published online Sep 7, 2014. doi: 10.3748/wjg.v20.i33.11916
Two cases of neuroendocrine carcinoma of the gallbladder
Hao Chen, Xing-Zhi Ni, Department of General Surgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China
Yan-Ying Shen, Department of Pathology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China
Author contributions: Chen H, Shen YY and Ni XZ contributed to the manuscript writing and revision; and all authors gave their approval for publishing this version of the manuscript.
Correspondence to: Xing-Zhi Ni, MD, Professor, Department of General Surgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, 1630 Dongfang Road, Shanghai 200127, China. niyin92@gmail.com
Telephone: +86-21-68383711 Fax: +86-21-58394262
Received: December 21, 2013
Revised: January 30, 2014
Accepted: March 8, 2014
Published online: September 7, 2014
Revised: January 30, 2014
Accepted: March 8, 2014
Published online: September 7, 2014
Core Tip
Core tip: The authors report two cases of neuroendocrine carcinoma of the gallbladder, which is an extremely rare disease. Both patients received radical surgery and showed responses to chemotherapy. The authors discuss possible approaches to improving prognosis including surgery, chemotherapy, radiotherapy and biological targeted therapy in the context of their experience and previously published studies.