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World J Gastroenterol. Aug 14, 2014; 20(30): 10504-10511
Published online Aug 14, 2014. doi: 10.3748/wjg.v20.i30.10504
Published online Aug 14, 2014. doi: 10.3748/wjg.v20.i30.10504
One fifth of hospitalizations for peptic ulcer-related bleeding are potentially preventable
Ray Boyapati, Sim Ye Ong, Bei Ye, Rhys Vaughan, Mayur Garg, Gastroenterology and Liver Transplant Unit, Austin Hospital, Melbourne, Victoria 3128, Australia
Anuk Kruavit, Nora Lee, Sanjay Nandurkar, Peter Gibson, Mayur Garg, Department of Gastroenterology and Hepatology, Eastern Health and Monash University, Melbourne, Victoria 3128, Australia
Peter Gibson, Department of Gastroenterology, The Alfred Hospital and Monash University, Melbourne, Victoria 3128, Australia
Author contributions: Boyapati R contributed to the collection of data, literature review, analysis of data, and writing of manuscript; Ong SY, Ye B, Kruavit A and Lee N contributed to the collection of data, review of manuscript; Vaughan R, Nandurkar S and Gibson P contributed to the intellectual planning, critical appraisal of manuscript; Garg M contributed to the intellectual planning, literature review, collection of data, analysis of data, writing and critical appraisal of the manuscript.
Correspondence to: Mayur Garg, Gastroenterologist, Department of Gastroenterology and Hepatology, Eastern Health and Monash University, Level 2, 5 Arnold St, Box Hill, Victoria 3128, Australia. mayur.garg@monash.edu
Telephone: +61-4-10624366 Fax: +61-3-98999137
Received: January 12, 2014
Revised: February 28, 2014
Accepted: April 21, 2014
Published online: August 14, 2014
Revised: February 28, 2014
Accepted: April 21, 2014
Published online: August 14, 2014
Core Tip
Core tip: Gastroprotective therapies reduce the risk of bleeding from peptic ulcer disease. For certain high risk groups, the risk reduction is significant: in the order of 50%-85%. Despite this, gastroprotection is still underutilised in this setting. It is unclear what proportion of hospitalizations that occur due to peptic ulcer disease bleeding is preventable. This original research finds that adherence to gastroprotective therapies in high risk populations is poor, and that up to one fifth of all hospitalizations due to peptic ulcer disease related bleeding are potentially preventable.