Topic Highlight
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World J Gastroenterol. Aug 14, 2014; 20(30): 10262-10278
Published online Aug 14, 2014. doi: 10.3748/wjg.v20.i30.10262
Inflammatory bowel disease in pediatric and adolescent patients: A biomolecular and histopathological review
Luciana Rigoli, Rosario Alberto Caruso
Luciana Rigoli, Department of Pediatrics, University of Messina, I-98125 Messina, Italy
Rosario Alberto Caruso, Department of Human Pathology, University of Messina, I-98125 Messina, Italy
Author contributions: Rigoli L and Caruso RA jointly contributed to this paper; Both authors read and approved the final version.
Correspondence to: Luciana Rigoli, MD, Department of Pediatrics, University of Messina, Via Consolare Valeria, 1, I-98125 Messina, Italy.
Telephone: +39-90-2212120 Fax: +39-90-2213788
Received: November 4, 2013
Revised: March 4, 2014
Accepted: April 15, 2014
Published online: August 14, 2014
Core Tip

Core tip: The review contains the most recent data of the literature and suggests a clinical- pathological heterogeneity of the inflammatory bowel disease (IBD) in childhood. It provides diagrams that display the main anatomo-clinical and biomolecular correlations and that may be encountered in IBD children. These diagnostic patterns and correlations may be useful in clinical practice for pediatric IBD.