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World J Gastroenterol. Jan 21, 2014; 20(3): 822-828
Published online Jan 21, 2014. doi: 10.3748/wjg.v20.i3.822
Published online Jan 21, 2014. doi: 10.3748/wjg.v20.i3.822
Impairment of secondary peristalsis in Barrett’s esophagus by transnasal endoscopy-based testing
Go Kobayashi, Department of Gastroenterology and Hepatology, Jikei University Daisan Hospital, Tokyo 201-8601, Japan
Mitsuru Kaise, Department of Gastroenterology, Toranomon Hospital, Tokyo 105-8470, Japan
Hiroshi Arakawa, Department of Endoscopy, Jikei University Kashiwa Hospital, Chiba 277-8567, Japan
Hisao Tajiri, Department of Gastroenterology and Hepatology, Jikei University School of Medicine, Tokyo 105-8461, Japan
Author contributions: Kobayashi G and Kaise M contributed equally to this work; Kobayashi G, Kaise M, Arakawa H and Tajiri H designed the research; Kobayashi G and Kaise M performed the research; Kobayashi G, Kaise M and Arakawa H analyzed the data; Kobayashi G, Kaise M and Tajiri H wrote the paper.
Correspondence to: Mitsuru Kaise, MD, Department of Gastroenterology, Toranomon Hospital, 2-2-2 Toranomon, Minato- ku, Tokyo 105-8470, Japan. kaise@toranomon.gr.jp
Telephone: +81-3-35881111 Fax: +81-3-35827068
Received: August 4, 2013
Revised: November 6, 2013
Accepted: December 3, 2013
Published online: January 21, 2014
Revised: November 6, 2013
Accepted: December 3, 2013
Published online: January 21, 2014
Core Tip
Core tip: We have developed a simple technique for esophageal examination based on transnasal endoscopy in unsedated patients. First, manometric waves and esophageal contractions were evaluated using three different modalities following the infusion of acid into the lower esophagus. Next, using nasal endoscopy, esophageal contractions and sensations were investigated in patients with Barrett’s esophagus. It was possible to observe secondary peristalsis endoscopically, using nasal endoscopy and a simple acid-perfusion study, we were able to demonstrate disorders in secondary peristalsis in patients with long segment Barrett’s esophagus.