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World J Gastroenterol. Jan 21, 2014; 20(3): 738-744
Published online Jan 21, 2014. doi: 10.3748/wjg.v20.i3.738
Solitary rectal ulcer syndrome: Clinical features, pathophysiology, diagnosis and treatment strategies
Qing-Chao Zhu, Rong-Rong Shen, Huan-Long Qin, Yu Wang
Qing-Chao Zhu, Yu Wang, Department of Surgery, The Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University, Shanghai 200233, China
Rong-Rong Shen, Huan-Long Qin, Department of Surgery, The Tenth People’s Hospital Affiliated to Shanghai Tongji University, Shanghai 200072, China
Author contributions: Zhu QC and Shen RR contributed equally to this work; Zhu QC and Shen RR wrote the manuscript; Qin HL collected and interpreted the data; Wang Y designed the review and revised the manuscript; all authors have read and approved the final manuscript.
Correspondence to: Yu Wang, Professor, Department of Surgery, The Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University, 600 Yishan Road, Shanghai 200233, China. yuwang11122@yahoo.com
Telephone: +86-21-64361349 Fax: +86-21-64368920
Received: September 26, 2013
Revised: November 10, 2013
Accepted: December 12, 2013
Published online: January 21, 2014
Core Tip

Core tip: We summarize the clinical features, pathophysiology, and diagnostic methods associated with solitary rectal ulcer syndrome (SRUS). Several therapies such as topical medication, behavior modification supplemented by fiber and biofeedback, and surgery are also discussed. The review might be conducive to understanding the nature of SRUS more systematically.