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World J Gastroenterol. Jul 28, 2014; 20(28): 9578-9584
Published online Jul 28, 2014. doi: 10.3748/wjg.v20.i28.9578
Published online Jul 28, 2014. doi: 10.3748/wjg.v20.i28.9578
Study of detection times for liver stiffness evaluation by shear wave elastography
Ze-Ping Huang, Xin-Ling Zhang, Jie Zeng, Jian Zheng, Ping Wang, Rong-Qin Zheng, Department of Medical Ultrasonics, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, Guangdong Province, China
Author contributions: Huang ZP and Zhang XL contributed equally to this work; Huang ZP and Zhang XL performed the majority of experiments and wrote the manuscript; Zeng J and Zheng J detected the patients and collected the data for this work; Wang P was involved in editing the manuscript; Zheng RQ designed the study.
Correspondence to: Rong-Qin Zheng, MD, PhD, Department of Medical Ultrasonics, the Third Affiliated Hospital of Sun Yat-sen University, No. 600 Tianhe Road, Guangzhou 510630, Guangdong Province, China. zhengrongqin@hotmail.com
Telephone: +86-20-85253030 Fax: +86-20-85252416
Received: October 13, 2013
Revised: April 20, 2014
Accepted: May 19, 2014
Published online: July 28, 2014
Revised: April 20, 2014
Accepted: May 19, 2014
Published online: July 28, 2014
Core Tip
Core tip: We evaluated the impact of different valid measurements (VMs) on the liver stiffness measurement by shear wave elastography in 112 chronic hepatitis B patients. Liver stiffness values obtained from 1 VM, 2 VMs, 3 VMs, 5 VMs and all 10 VMs were similar, and there were no significant differences between these groups. The repeatability was excellent among different pathological stages in different groups. The mean elasticity values can accurately distinguish fibrosis stages with no significant differences seen in the five groups. One VM may be enough to assess liver fibrosis using shear wave elastography without any significant loss of accuracy.