Case Control Study
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World J Gastroenterol. Jul 28, 2014; 20(28): 9541-9548
Published online Jul 28, 2014. doi: 10.3748/wjg.v20.i28.9541
Association of metabolic syndromes and risk factors with ampullary tumors development: A case-control study in China
Xiao-Dong He, Qiao Wu, Wei Liu, Tao Hong, Jing-Jing Li, Ruo-Yu Miao, Hai-Tao Zhao
Xiao-Dong He, Qiao Wu, Wei Liu, Tao Hong, Jing-Jing Li, Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
Ruo-Yu Miao, Hai-Tao Zhao, Department of Liver Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
Author contributions: Zhao HT contributed to the conception of the study and designed the protocol; He XD and Wu Q performed clinical data acquisition, the statistical analysis and data interpretation; He XD, Wu Q and Zhao HT wrote the manuscript; Liu W, Hong T, Li JJ and Miao RY helped perform the analysis with constructive discussions; He XD and Wu Q contributed equally to this work.
Supported by A grant (in part) from the Municipal Key Discipline of Beijing, China, No. HK100230446; the National Natural Science Foundation of China, No. 81372578; International Science and Technology Cooperation Projects, No. 2010DFB33720; Program for New Century Excellent Talents in University, No. NCET-11-0288
Correspondence to: Hai-Tao Zhao, MD, Department of Liver Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China. pumchzht@aliyun.com
Telephone: +86-10-69156024 Fax: +86-10-69156010
Received: November 5, 2013
Revised: February 22, 2014
Accepted: May 19, 2014
Published online: July 28, 2014
Core Tip

Core tip: Although ampullary tumors are relatively rare, the rapid development of, and advances in, endoscopy and imaging techniques have profoundly increased their discovery rate. Despite the increasing numbers of published studies, the etiology for ampullary tumors is incompletely defined. This is the first study to evaluate the impact of metabolic syndromes on ampullary tumors patients.