Topic Highlight
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World J Gastroenterol. Jul 21, 2014; 20(27): 8971-8978
Published online Jul 21, 2014. doi: 10.3748/wjg.v20.i27.8971
Natural products and food components with anti-Helicobacter pylori activities
Hiroaki Takeuchi, Vu Thu Trang, Norihito Morimoto, Yoshie Nishida, Yoshihisa Matsumura, Tetsuro Sugiura
Hiroaki Takeuchi, Norihito Morimoto, Yoshie Nishida, Yoshihisa Matsumura, Tetsuro Sugiura, Department of Clinical Laboratory Medicine, Kochi Medical School, Kochi 783-8505, Japan
Vu Thu Trang, School of Biotechnology and Food Technology, Hanoi University of Science and Technology, Hanoi 12771, Vietnam
Author contributions: Takeuchi H designed and performed research, and wrote the paper; Trang VT performed research and contributed analytic tools; Morimoto N and Nishida Y contributed analytic tools; Matsumura Y and Sugiura T analyzed data.
Supported by JSPS KAKENHI Grant, No. 24590697 and No. 24590698; and the Vietnam National Foundation for Science and Technology Development (NAFOSTED, 106.99-2011.22)
Correspondence to: Hiroaki Takeuchi, PhD, Department of Clinical Laboratory Medicine, Kochi Medical School, Kohasu, Oko-cho, Nankoku-city, Kochi 783-8505, Japan. htake@kochi-u.ac.jp
Telephone: +81-88-8802427 Fax: +81-88-8802428
Received: September 27, 2013
Revised: January 20, 2014
Accepted: April 1, 2014
Published online: July 21, 2014
Core Tip

Core tip: The present review summarized the natural products and food components with anti-Helicobacter pylori (H. pylori) activities in the literatures and showed the possibility for its application on human health. There are many promising in vitro effects on H. pylori and other infections (infectious diseases). Next, further in vivo evidence is required. There are many guidelines for H. pylori treatment which are not always the same among countries. Thus, we should address the evaluation of in vivo effects using such components in clinical investigation to make an adequate guideline useful for all countries for the application on H. pylori treatment.