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©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 7, 2014; 20(25): 8282-8287
Published online Jul 7, 2014. doi: 10.3748/wjg.v20.i25.8282
Published online Jul 7, 2014. doi: 10.3748/wjg.v20.i25.8282
Endoscopic submucosal dissection vs endoscopic mucosal resection for colorectal tumors: A meta-analysis
Jing Wang, Xiao-Hua Zhang, Jian Ge, Chong-Mei Yang, Ji-Yong Liu, Shu-Lei Zhao, Department of Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan 250021, Shandong Province, China
Author contributions: Zhao SL proposed the study; Zhao SL, Wang J, Zhang XH, Ge J, Yang CM, Liu JY performed the research and drafted the paper; Wang J collected and analyzed the data; all authors contributed to the design and interpretation of the study and further revision of the paper; Zhao SL is the supervisor.
Correspondence to: Shu-Lei Zhao, MD, Department of Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong University, 324 Jingwu Weiqi Rd, Jinan 250021, Shandong Province, China. wenzhu24@126.com
Telephone: +86-531-87987938 Fax: +86-531-87987938
Received: December 26, 2013
Revised: February 27, 2014
Accepted: April 21, 2014
Published online: July 7, 2014
Revised: February 27, 2014
Accepted: April 21, 2014
Published online: July 7, 2014
Core Tip
Core tip: Endoscopic submucosal dissection (ESD) was originally developed for en bloc resection of lager, flat gastrointestinal tumors. Compared with endoscopic mucosal resection (EMR), ESD was considered to be more time consuming and have more complications for the treatment of colorectal tumors. This meta-analysis of six trials shows that compared with EMR, ESD gives higher en bloc resection rate and lower local recurrence rate for the treatment of colorectal tumors, without increasing the procedure-related complications. ESD should be considered in the endoscopic treatment of colorectal tumors.