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World J Gastroenterol. Jun 21, 2014; 20(23): 7231-7241
Published online Jun 21, 2014. doi: 10.3748/wjg.v20.i23.7231
Noninvasive diagnosis of cirrhosis: A review of different imaging modalities
Riccardo De Robertis, Mirko D’Onofrio, Emanuele Demozzi, Stefano Crosara, Stefano Canestrini, Roberto Pozzi Mucelli
Riccardo De Robertis, Mirko D’Onofrio, Emanuele Demozzi, Stefano Crosara, Stefano Canestrini, Roberto Pozzi Mucelli, Department of Radiology, G.B. Rossi Hospital, University of Verona, 37134 Verona, Italy
Author contributions: All authors equally contributed to this paper; D’Onofrio M and Pozzi Mucelli R designed the research and gave their final approval for submission; Demozzi E, Crosara S and Canestrini S performed the research and revised the paper; De Robertis R performed the research, wrote and revised the paper.
Correspondence to: Riccardo De Robertis, MD, Department of Radiology, G.B. Rossi Hospital, University of Verona, Piazzale L.A. Scuro 10, 37134 Verona, Italy. riccardo.derobertis@hotmail.it
Telephone: +39-45-8124301 Fax: +39-45-8027490
Received: October 27, 2013
Revised: January 8, 2014
Accepted: April 8, 2014
Published online: June 21, 2014
Core Tip

Core tip: In order to overcome the well-known drawbacks of liver biopsy, different non-invasive imaging tests have been developed for diagnosing and staging liver fibrosis. At present, transient elastography and acoustic radiation force impulse imaging are the most widely used. Reviewing literature, it seems that acoustic radiation force impulse imaging, having the advantage of being included in ultrasound equipments, could provide higher reproducibility and successful measurements rate, with a more precise examination than transient elastography. Magnetic resonance-based methods, especially hepatospecific contrast medium uptake/excretion measurements and elastography, are promising but still not universally available tools.