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©2014 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastroenterol. Jan 14, 2014; 20(2): 445-459
Published online Jan 14, 2014. doi: 10.3748/wjg.v20.i2.445
Published online Jan 14, 2014. doi: 10.3748/wjg.v20.i2.445
Non-invasive diagnosis of hepatitis B virus-related cirrhosis
Sangheun Lee, Do Young Kim, Department of Internal Medicine, Yonsei University College of Medicine, Seoul 120-752, South Korea
Do Young Kim, Liver Cirrhosis Clinical Research Center, Seoul 120-752, South Korea
Author contributions: Lee S and Kim DY contributed to this work; Kim DY designed research; Lee S and Kim DY performed research; and Lee S wrote the paper.
Supported by A grant of the South Korea Healthcare technology R and D project, Ministry of Health and Welfare, South Korea, No. HI10C2020
Correspondence to: Do Young Kim, MD, Department of Internal Medicine, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-752, South Korea. dyk1025@yuhs.ac
Telephone: +82-2-22281992 Fax: +82-2-3936884
Received: October 25, 2013
Revised: November 25, 2013
Accepted: December 5, 2013
Published online: January 14, 2014
Revised: November 25, 2013
Accepted: December 5, 2013
Published online: January 14, 2014
Core Tip
Core tip: Chronic hepatitis B (CHB) infection is associated with significant morbidity and mortality because it can progress to cirrhosis or hepatocellular carcinoma. Early diagnosis of liver cirrhosis in CHB patients is important to prevent the disease progression. Non-invasive diagnosis has been developed remarkably and showed high diagnostic accuracy for cirrhosis. New methods and the combination of non-invasive diagnosis tools may contribute to the improvement to diagnose the cirrhosis with CHB.