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World J Gastroenterol. May 21, 2014; 20(19): 5639-5653
Published online May 21, 2014. doi: 10.3748/wjg.v20.i19.5639
Role of dental plaque, saliva and periodontal disease in Helicobacter pylori infection
Pradeep S Anand, Kavitha P Kamath, Sukumaran Anil
Pradeep S Anand, Department of Periodontics, People’s College of Dental Sciences and Research Centre, Bhopal, Madhya Pradesh 462037, India
Kavitha P Kamath, Department of Oral Pathology, People’s Dental Academy, Bhopal, Madhya Pradesh 462037, India
Sukumaran Anil, Department of Periodontics and Community Dentistry, College of Dentistry, King Saud University, Riyadh 11545, Saudi Arabia
Author contributions: Anand PS contributed to the conception and design of the paper and edited the final version of the article for approval; Anand PS, Kamath KP, and Anil S performed the literature search, reviewed the literature, and prepared the draft version; Anand PS and Kamath KP revised and edited the draft version for intellectual content.
Correspondence to: Pradeep S Anand, MDS, Department of Periodontics, People’s College of Dental Sciences and Research Centre, Bhanpur Bypass Road, Bhanpur, Bhopal, Madhya Pradesh 462037, India.
Telephone: +91-998-1511098 Fax: +91-755-4005315
Received: September 28, 2013
Revised: January 19, 2014
Accepted: March 6, 2014
Published online: May 21, 2014
Core Tip

Core tip:Helicobacter pylori (H. pylori) infection is one of the most common bacterial infections in humans. The mode of transmission of this bacterium has long puzzled researchers. Numerous studies have shown that this microorganism can be detected in dental plaque and saliva of human subjects, suggesting that the oral cavity may be an extra-gastric reservoir of H. pylori and play an important role in both transmission and recurrence. Recent data support this hypothesis and indicate that periodontal therapy may play a role in the management of H. pylori-associated gastric disease.