Observational Study
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World J Gastroenterol. May 14, 2014; 20(18): 5527-5532
Published online May 14, 2014. doi: 10.3748/wjg.v20.i18.5527
Negative impact of sedation on esophagogastric junction evaluation during esophagogastroduodenoscopy
Eun Soo Kim, Ho Young Lee, Yoo Jin Lee, Bo Ram Min, Jae Hyuk Choi, Kyung Sik Park, Kwang Bum Cho, Byoung Kuk Jang, Woo Jin Chung, Jae Seok Hwang
Eun Soo Kim, Ho Young Lee, Yoo Jin Lee, Bo Ram Min, Jae Hyuk Choi, Kyung Sik Park, Kwang Bum Cho, Byoung Kuk Jang, Woo Jin Chung, Jae Seok Hwang, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keimyung University School of Medicine, Daegu 700-712, South Korea
Author contributions: Park KS and Kim ES designed the research; Kim ES, Lee YJ, Cho KB, Jang BK, Choi JH and Min BR performed the research; Chung WJ, Hwang JS and Park KS analyzed the data; Kim ES and Lee HY wrote the paper; Kim ES and Lee HY contributed equally to this work.
Correspondence to: Kyung Sik Park, MD, PhD, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keimyung University School of Medicine, 194 Dong San-dong, Jung-gu, Daegu 700-712, South Korea. seenae99@dsmc.or.kr
Telephone: +82-53-2508096 Fax: +82-53-2507088
Received: December 27, 2013
Revised: February 18, 2014
Accepted: March 6, 2014
Published online: May 14, 2014
Core Tip

Core tip: The development of clinically important lesions located in the esophagogastric junction (EGJ), such as gastroesophageal reflux disease, Barrett’s esophagus, and esophageal adenocarcinoma are increasing. The vast majority of endoscopies are performed with sedation and this practice seems likely to continue. Therefore, it is clinically relevant to evaluate the impact of sedation on inspection of the EGJ during esophagogastroduodenoscopy (EGD). We found that sedation during EGD has a negative impact on EGJ evaluation. It remains to be seen whether this negative impact affects the detection rate of EGJ lesions.