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World J Gastroenterol. May 14, 2014; 20(18): 5235-5243
Published online May 14, 2014. doi: 10.3748/wjg.v20.i18.5235
Published online May 14, 2014. doi: 10.3748/wjg.v20.i18.5235
Cytokines, cytokine gene polymorphisms and Helicobacter pylori infection: Friend or foe?
Camila A Figueiredo, Cintia Rodrigues Marques, Ryan dos Santos Costa, Hugo Bernardino F da Silva, Neuza M Alcantara-Neves, Instituto de Ciências da Saúde, Universidade Federal da Bahia, Salvador, Bahia 41110-100, Brazil
Author contributions: Figueiredo CA contributed to the conception and design of the article, revised and edited the draft for intellectual content and gave final approval of the submitted version; Marques CR, Costa RS and Silva HBF reviewed the literature and wrote the manuscript draft; and Alcantara-Neves NM contributed to the manuscript’s conception and reviewed and edited the final version of the article.
Correspondence to: Neuza M Alcantara-Neves, MD, PhD, Instituto de Ciências da Saúde, Universidade Federal da Bahia, Av. Reitor Miguel Calmon, S/N, Canela, CEP 40110-100, Salvador, Bahia, Brazil. neuzalcantara@gmail.com
Telephone: +55-71-32838932 Fax: +55-71-32838932
Received: September 28, 2013
Revised: December 11, 2013
Accepted: January 8, 2014
Published online: May 14, 2014
Revised: December 11, 2013
Accepted: January 8, 2014
Published online: May 14, 2014
Core Tip
Core tip: In this review, we present the cytokine profiles of infection and the main cytokine gene polymorphisms associated with resistance/susceptibility to Helicobacter pylori. We also discuss how such polymorphisms may influence infection/disease outcomes.