Published online Apr 7, 2014. doi: 10.3748/wjg.v20.i13.3640
Revised: November 9, 2013
Accepted: December 12, 2013
Published online: April 7, 2014
Core tip: The number of metastatic lymph nodes has been shown to be associated with prognosis in gastric cancer patients. In this study, we found that the overall survival of node-negative gastric cancer patients was significantly affected by examined lymph nodes (eLNs), and number of eLNs was an independent prognostic factor in multivariate analysis. Dissection of > 15 eLNs could reduce locoregional and peritoneal recurrence. We suggest that over 15 lymph nodes should be examined to improve the long-term outcome of node-negative gastric cancer patients following curative gastrectomy.