Research Report
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World J Gastroenterol. Apr 7, 2014; 20(13): 3635-3639
Published online Apr 7, 2014. doi: 10.3748/wjg.v20.i13.3635
Seroepidemiology of Helicobacter pylori infection in elderly people in the Beijing region, China
Mei Zhang, Ying-Zhi Zhou, Xiao-Ying Li, Zhe Tang, Hong-Ming Zhu, Yan Yang, Jagadish K Chhetri
Mei Zhang, Ying-Zhi Zhou, Xiao-Ying Li, Zhe Tang, Hong-Ming Zhu, Yan Yang, Jagadish K Chhetri, Department of Gastroenterology, XuanWu Hospital, Capital Medical University, Beijing 100053, China
Author contributions: Zhang M conceived the study and drafted the paper; Li XY approved and supervised the paper; Zhou YZ and Chhetri JK critically reviewed and revised the paper; Tang Z collected source material and analyzed the preliminary data; Zhu HM and Yang Y analyzed the data and performed the statistics.
Correspondence to: Mei Zhang, Professor, Department of Gastroenterology, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xuanwu District, Beijing100053, China. zhang2955@sina.com
Telephone: +86-10-83198899 Fax: +86-10-83198899
Received: February 13, 2014
Revised: February 25, 2014
Accepted: March 5, 2014
Published online: April 7, 2014
Core Tip

Core tip: As society ages, a considerable proportion of the elderly population will suffer from digestive diseases combined with Helicobacter pylori (H. pylori) infection. In Beijing, there are no data regarding the pattern of H. pylori genotypes in the elderly. Our study investigated the seroepidemiology of the cytotoxin-associated gene product cagA+ and vacuolating cytotoxin vacA+ strains of H. pylori in elderly people in Beijing, and risk factors for seropositivity. Interesting associations between H. pylori seropositivity and subjects’ habits were found in this population. This is the first prospective study conducted in China to investigate the genotype profiles of H. pylori.