Published online Apr 7, 2014. doi: 10.3748/wjg.v20.i13.3572
Revised: October 23, 2013
Accepted: January 2, 2014
Published online: April 7, 2014
Core tip: Ischemia-reperfusioin injury, which commonly occurs during transplant procedures, is associated with inflammatory cytokine release, endothelial dysfunction and oxidative stress. Remote ischemic-preconditioning is a procedure that can attenuate all of these alterations. The pathophysiology of many non-ischemic gastrointestinal disorders, such as radiation-induced enteritis and inflammatory bowel disease, among others, involves many of these same mechanisms. Future research should address the question of whether remote ischemic-preconditioning could also favorably alter the course of these diseases.