Hepatitis B and C virus reactivation in immunosuppressed patients with inflammatory bowel disease

doi:10.3748/wjg.v20.i13.3516

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Apr 7, 2014 (publication date) through Apr 26, 2024

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World Journal of Gastroenterology

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1007-9327

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World J Gastroenterol. Apr 7, 2014; 20(13): 3516-3524
Published online Apr 7, 2014. doi: 10.3748/wjg.v20.i13.3516

Hepatitis B and C virus reactivation in immunosuppressed patients with inflammatory bowel disease

Stefano Sansone, Maria Guarino, Fabiana Castiglione, Antonio Rispo, Francesco Auriemma, Ilaria Loperto, Matilde Rea, Nicola Caporaso, Filomena Morisco

Stefano Sansone, Maria Guarino, Fabiana Castiglione, Antonio Rispo, Francesco Auriemma, Ilaria Loperto, Matilde Rea, Nicola Caporaso, Filomena Morisco, Gastroenterology Unit, Department of Clinical Medicine and Surgery, University of Naples “Federico II”, 80131 Naples, Italy

Author contributions: Sansone S, Guarino M and Morisco F wrote the paper; all authors made a substantial contribution to interpretation of the data, revised the manuscript critically for important intellectual content and approved the final version to be published.

Correspondence to: Filomena Morisco, Professor, Gastroenterology Unit, Department of Clinical Medicine and Surgery, University of Naples “Federico II”, via Sergio Pansini, 5, 80131 Napoli, Italy. filomena.morisco@unina.it

Telephone: +39-81-7464746 Fax: +39-81-7464746

Received: September 28, 2013
Revised: December 13, 2013
Accepted: March 6, 2014
Published online: April 7, 2014

Core Tip

Core tip: Our review focused on the redundancy of papers on hepatitis B virus and hepatitis C virus reactivation in patients undergoing immunosuppressive therapy. However, we emphasize that, to date, very few clinical studies have been published, and most of them were retrospective with conflicting results. Thus, it is essential to conduct prospective studies before performing additional reviews of the literature.