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World J Gastroenterol. Dec 7, 2013; 19(45): 8382-8390
Published online Dec 7, 2013. doi: 10.3748/wjg.v19.i45.8382
Published online Dec 7, 2013. doi: 10.3748/wjg.v19.i45.8382
Primary adenosquamous carcinoma of the esophagus
Shao-Bin Chen, Hong-Rui Weng, Geng Wang, Jie-Sheng Yang, Wei-Ping Yang, Di-Tian Liu, Yu-Ping Chen, Department of Thoracic Surgery, Cancer Hospital of Shantou University Medical College, Shantou 515031, Guangdong Province, China
Hao Zhang, Department of Integrative Oncology, Cancer Hospital of Shantou University Medical College, Shantou 515031, Guangdong Province, China
Hao Zhang, Cancer Research Centre, Shantou University Medical College, Shantou 515031, Guangdong Province, China
Author contributions: Chen YP designed the research; Chen SB analyzed the data and wrote the paper; Chen SB, Weng HR, Wang G, Yang JS, Yang WP, Liu DT and Zhang H performed the research.
Correspondence to: Yu-Ping Chen, MD, Professor, Department of Thoracic Surgery, Cancer Hospital of Shantou University Medical College, 7 Raoping Road, Shantou 515031, Guangdong Province, China. stchenyp@hotmail.com
Telephone: +86-754-88555844 Fax: +86-754-88560352
Received: August 1, 2013
Revised: September 22, 2013
Accepted: October 19, 2013
Published online: December 7, 2013
Revised: September 22, 2013
Accepted: October 19, 2013
Published online: December 7, 2013
Core Tip
Core tip: Primary adenosquamous carcinoma (ASC) of the esophagus is an uncommon malignant esophageal neoplasm containing coexisting elements of infiltrating squamous cell carcinoma and adenocarcinoma. The biological behavior and response to therapies of this disease have not been well studied. In the current study, we reported the largest ever single-center patient cohort undergoing surgical resection for primary esophageal ASC, and we investigated the clinical characteristics, diagnosis, treatment, and prognosis in these patients. These data will give us a better understanding of this disease and help select the proper strategy for therapy.