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World J Gastroenterol. Nov 21, 2013; 19(43): 7804-7812
Published online Nov 21, 2013. doi: 10.3748/wjg.v19.i43.7804
Published online Nov 21, 2013. doi: 10.3748/wjg.v19.i43.7804
Is Dor fundoplication optimum after laparoscopic Heller myotomy for achalasia? A meta-analysis
Ming-Tian Wei, Ya-Zhou He, Xiang-Bing Deng, Yuan-Chuan Zhang, Ting-Han Yang, Cheng-Wu Jin, Zi-Qiang Wang, Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
Bing Hu, Endoscopic Center, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
Author contributions: Wang ZQ and Wei MT designed the research; Wang ZQ and Hu B provided supervision; Wei MT, He YZ and Deng XB performed the research; Zhang YC, Yang TH and Jin CW performed a literature search and collected the data; Wei MT and He YZ analyzed the data and wrote the paper.
Supported by National Natural Science Foundation of China, Grant 81172373
Correspondence to: Zi-Qiang Wang, Professor, Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, No. 37 Guo Xue Alley, Chengdu 610041, Sichuan Province, China. wangzqzyh@163.com
Telephone: +86-28-85422480 Fax: +86-28-81654035
Received: July 14, 2013
Revised: August 24, 2013
Accepted: September 16, 2013
Published online: November 21, 2013
Revised: August 24, 2013
Accepted: September 16, 2013
Published online: November 21, 2013
Core Tip
Core tip: Laparoscopic Heller myotomy (LHM) is commonly used to treat achalasia and an antireflux procedure is added after LHM for prevention of gastroesophageal reflux (GER). However, there is no consensus on whether Dor fundoplication is the optimum procedure after LHM for the prevention of GER. We conducted this meta-analysis to assess Dor fundoplication compared with non-fundoplication surgery or other types of fundoplication surgery for achalasia. The results indicated higher recurrence rate of clinical regurgitation and pathological acid reflux in Dor fundoplication indicating that Dor fundoplication is not the optimum procedure for the prevention of GER after LHM in achalasia patients.