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World J Gastroenterol. Nov 21, 2013; 19(43): 7652-7660
Published online Nov 21, 2013. doi: 10.3748/wjg.v19.i43.7652
Published online Nov 21, 2013. doi: 10.3748/wjg.v19.i43.7652
Use of exclusive enteral nutrition in adults with Crohn’s disease: A review
Catherine L Wall, Andrew S Day, Department of Paediatrics, University of Otago, Christchurch 8140, New Zealand
Richard B Gearry, Department of Medicine, University of Otago, Christchurch 8140, New Zealand
Author contributions: Wall CL collected and collated the data and drafted the manuscript; Day AS and Gearry RB conceived the article idea, participated in its design and contributed to draft manuscripts; All authors read and approved the final manuscript.
Correspondence to: Andrew S Day, Professor, Department of Paediatrics, University of Otago, Christchurch, 2 Riccarton Ave, PO Box 4345, Christchurch 8140, New Zealand. andrew.day@otago.ac.nz
Telephone: +64-3-3640747 Fax: +64-3-3786355
Received: May 24, 2013
Revised: July 20, 2013
Accepted: September 16, 2013
Published online: November 21, 2013
Revised: July 20, 2013
Accepted: September 16, 2013
Published online: November 21, 2013
Core Tip
Core tip: Exclusive enteral nutrition (EEN) is an established treatment for children with active Crohn’s disease (CD). At present, this therapy is used sparingly in adult patients outside of Japan. In reviewing the published literature regarding the use of EEN in adult patients, this article highlights evidence supporting the use of EEN as a treatment option for selected patients: namely those motivated to adhere to an EEN regimen and those newly diagnosed with CD. The role of EEN in adult patients with CD should now be re-examined, with particular regard to treatment protocols and the use of more palatable polymeric formulae that may enhance compliance.