Brief Article
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World J Gastroenterol. Oct 21, 2013; 19(39): 6645-6650
Published online Oct 21, 2013. doi: 10.3748/wjg.v19.i39.6645
Can eradication rate of gastric Helicobacter pylori be improved by killing oral Helicobacter pylori?
Han-Yi Song, Yan Li
Han-Yi Song, Yan Li, Department of Gastroenterology, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning Province, China
Author contributions: Song HY designed the study, analyzed the data and wrote the manuscript; Song HY and Li Y carried out the study; Li Y contributed the reagents and analytic tools.
Correspondence to: Yan Li, MD, PhD, Chief of Department of Gastroenterology, Shengjing Hospital of China Medical University, Floor 14, Unit A, 1st Building, Sanhao Street, Heping District, Shenyang 110004, Liaoning Province, China. Yanli0227@126.com
Telephone: +86-24-966152-6111 Fax: +86-24-966152-6111
Received: February 17, 2013
Revised: June 1, 2013
Accepted: July 4, 2013
Published online: October 21, 2013
Core Tip

Core tip: The average eradication rate of gastric Helicobacter pylori (H. pylori) has decreased in recent years. However, some foreign studies have shown that the eradication rate of gastric H. pylori may be improved by eliminating the presence of oral H. pylori rather than increasing the dose of antibiotics. In most studies, H. pylori DNA was detected and used to confirm oral H. pylori infection, and later determine whether professional periodontal treatments were effective in killing oral H. pylori. To avoid the expensive and complicated techniques involved with this approach, the current study used a cost-effective and simple method to test for and eliminate oral H. pylori. This method can be used to prove the elimination of gastric H. pylori, and is practical for use in the clinic.