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World J Gastroenterol. Sep 28, 2013; 19(36): 6077-6083
Published online Sep 28, 2013. doi: 10.3748/wjg.v19.i36.6077
Published online Sep 28, 2013. doi: 10.3748/wjg.v19.i36.6077
Up-to-seven criteria for hepatocellular carcinoma liver transplantation: A single center analysis
Jian-Yong Lei, Wen-Tao Wang, Lu-Nan Yan, Liver Transplantation Center, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China
Author contributions: Wang WT proposed the study and was the guarantor; Wang WT and Lei JY performed research and wrote the first draft; Lei JY collected and analyzed the data; all authors contributed to the design and interpretation of the study and to further drafts.
Correspondence to: Wen-Tao Wang, MD, PhD, Liver Transplantation Center, West China Hospital of Sichuan University, 29 Wangjiang Road, Chengdu 610041, Sichuan Province, China. ljydoctor@163.com
Telephone: +86-28-85422867 Fax: +86-28-85422867
Received: July 14, 2013
Revised: August 15, 2013
Accepted: August 20, 2013
Published online: September 28, 2013
Revised: August 15, 2013
Accepted: August 20, 2013
Published online: September 28, 2013
Core Tip
Core tip: The up-to-seven criteria were introduced several years ago, but there is still no consensus about their effectiveness. Two hundred and twenty patients were divided into three groups according to the characteristics of their tumors: the 1-, 3-, and 5-year overall survival and tumor-free survival rate for the Milan criteria group were higher than that in the up-to-seven criteria group. However, the advanced hepatocellular carcinoma patients’ overall and tumor-free survival rates were much lower. So considering that patients in the up-to-seven criteria group exhibited a considerable but lower survival rate compared with the Milan criteria group, the up-to-seven criteria should be used carefully and selectively.