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World J Gastroenterol. Sep 7, 2013; 19(33): 5542-5550
Published online Sep 7, 2013. doi: 10.3748/wjg.v19.i33.5542
Published online Sep 7, 2013. doi: 10.3748/wjg.v19.i33.5542
Impact of intraoperative blood loss on survival after curative resection for gastric cancer
Yue-Xiang Liang, Jing-Yu Deng, Bao-Gui Wang, Xue-Wei Ding, Xiao-Na Wang, Li Zhang, Han Liang, Key Laboratory of Cancer Prevention and Therapy, Tianjin 300060, China
Yue-Xiang Liang, Jing-Yu Deng, Bao-Gui Wang, Xue-Wei Ding, Xiao-Na Wang, Li Zhang, Han Liang, Department of Gastric Cancer, Tianjin Medical University Cancer institute and hospital, Tianjin 300060, China
Han-Han Guo, Department of Cardiovascular Surgery, the First Hospital of Tianshui City, Tianshui 741000, Gansu Province, China
Author contributions: Liang YX, Guo HH and Liang H performed the majority of the study; Guo HH, Deng JY, Wang BG, Ding XW, Wang XN and Zhang L designed the study and analyzed data; Liang YX, Guo HH, Wang BG and Liang H wrote the manuscript; Wang BG, Deng JY, Ding XW and Wang XN revised the manuscript.
Correspondence to: Dr. Han Liang, Department of Gastric Cancer, Tianjin Medical University Cancer institute and hospital, Huanhuxi Road, Hexi District, Tianjin 300060, China. tjlianghan@sohu.com
Telephone: +86-22-23340123 Fax: +86-22-23340123
Received: May 16, 2013
Revised: July 10, 2013
Accepted: July 17, 2013
Published online: September 7, 2013
Revised: July 10, 2013
Accepted: July 17, 2013
Published online: September 7, 2013
Core Tip
Core tip: Intraoperative blood loss (IBL) has been shown to be associated with poor outcome in various types of malignancy. In this study, we found that the overall survival of gastric cancer patients was significantly affected by the amount of IBL, and IBL was an independent prognostic factor in multivariate analysis. We suggest that meticulous surgery and new surgical methods such as the application of an ultrasonic scalpel in lymph node dissection should be used to decrease the amount of IBL and improve the long-term outcome of gastric cancer patients following curative gastrectomy.