Review
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World J Gastroenterol. Aug 14, 2013; 19(30): 4867-4876
Published online Aug 14, 2013. doi: 10.3748/wjg.v19.i30.4867
MicroRNAs may solve the mystery of chronic hepatitis B virus infection
Ying-Feng Wei, Guang-Ying Cui, Ping Ye, Jia-Ning Chen, Hong-Yan Diao
Ying-Feng Wei, Guang-Ying Cui, Ping Ye, Jia-Ning Chen, Hong-Yan Diao, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medical, Zhejiang University, Hangzhou 310003, Zhejiang Province, China
Author contributions: Diao HY directed the paper; Wei YF collected the date and wrote the paper; Cui GY, Ye P and Chen JN took part in the revising of this paper.
Supported by The National Natural Science Foundation of China, No. 81271810; 12-5 state S and T Projects for infectious diseases, No. 2012ZX10002-007; Doctoral Fund of Ministry of Education of China, No. 20120101110009; the National Basic Research Program, No. 2013CB531405
Correspondence to: Hong-Yan Diao, MD, PhD, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, the First Affiliated Hospital, School of Medicine, Zhejiang University, 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. diaohy@zju.edu.cn
Telephone: +86-571-87236446 Fax: +86-571-87236446
Received: April 6, 2013
Revised: June 4, 2013
Accepted: July 4, 2013
Published online: August 14, 2013
Core Tip

Core tip: The cellular microRNAs (miRNAs) involved in host-hepatitis B virus (HBV) interaction and each stage of HBV-related disease show distinctive miRNA expression profiles at the tissue or serum level indicating that miRNAs have marked potential in detecting or treating of HBV infection.