Published online Aug 7, 2013. doi: 10.3748/wjg.v19.i29.4752
Revised: May 30, 2013
Accepted: June 8, 2013
Published online: August 7, 2013
Core tip: Tissue acquisition from subepithelial tumors (SETs) is essential for a differential diagnosis. Several techniques have been introduced to obtain SET tissue samples. However, the diagnostic efficacy was limited or the procedure was complex and difficult. We investigated a modified technique for the histological diagnosis of SETs, consisting of a mucosal incision with a fixed flexible snare (MIF) and deep-tissue biopsy at the incision site under a conventional endoscopic view. The results of this study suggest that the MIF biopsy is simple to perform, safe, fast, and provides a high diagnostic yield for small SETs.