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World J Gastroenterol. Aug 7, 2013; 19(29): 4752-4757
Published online Aug 7, 2013. doi: 10.3748/wjg.v19.i29.4752
Published online Aug 7, 2013. doi: 10.3748/wjg.v19.i29.4752
A feasible modified biopsy method for tissue diagnosis of gastric subepithelial tumors
Jung Ho Kim, Jun-Won Chung, Minsu Ha, Min Young Rim, Jong Joon Lee, Yoon Jae Kim, Kyoung Oh Kim, Kwang An Kwon, Dong Kyun Park, Yeon Suk Kim, Duck Joo Choi, Department of Internal Medicine, Gachon University Gil Medical Center, Incheon 405-760, South Korea
Jungsuk An, Department of Pathology, Gachon University Gil Medical Center, Incheon 405-760, South Korea
Author contributions: Chung JW designed the research and performed procedure of modified biopsy; Kim JH and Ha M performed research; Rim MY, Lee JJ and Kim KO collected data; An J and Kim YJ analysed data; Kwon KA, Park DK and Kim YS coordinated and supported the statistical analysis; Kim JH wrote the paper; Choi DJ prepared the figures.
Correspondence to: Jun-Won Chung, MD, PhD, Department of Internal Medicine, Gachon University Gil Medical Center, 1198 Guwol-dong, Namdong-Gu, Incheon 405-760, South Korea. drgreen@gilhospital.com
Telephone: +82-32-4603778 Fax: +82-32-4603408
Received: April 3, 2013
Revised: May 30, 2013
Accepted: June 8, 2013
Published online: August 7, 2013
Revised: May 30, 2013
Accepted: June 8, 2013
Published online: August 7, 2013
Core Tip
Core tip: Tissue acquisition from subepithelial tumors (SETs) is essential for a differential diagnosis. Several techniques have been introduced to obtain SET tissue samples. However, the diagnostic efficacy was limited or the procedure was complex and difficult. We investigated a modified technique for the histological diagnosis of SETs, consisting of a mucosal incision with a fixed flexible snare (MIF) and deep-tissue biopsy at the incision site under a conventional endoscopic view. The results of this study suggest that the MIF biopsy is simple to perform, safe, fast, and provides a high diagnostic yield for small SETs.