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World J Gastroenterol. Jul 28, 2013; 19(28): 4520-4525
Published online Jul 28, 2013. doi: 10.3748/wjg.v19.i28.4520
Published online Jul 28, 2013. doi: 10.3748/wjg.v19.i28.4520
Negative capsule endoscopy in patients with obscure gastrointestinal bleeding reliable: Recurrence of bleeding on long-term follow-up
Maria Elena Riccioni, Guido Costamagna, Digestive Endoscopy Unit, Catholic University of Rome, 00168 Rome, Italy
Riccardo Urgesi, Gastroenterology and Digestive Endoscopy Unit, Ospedale Belcolle, 01100 Viterbo, Italy
Rossella Cianci, Department of Internal Medicine, Catholic University of Rome, 00168 Rome, Italy
Gianluca Rizzo, Department of Surgery, Catholic University of Rome, 00168 Rome, Italy
Luca D’Angelo, Department of Neurosurgery, Ospedale Belcolle, 01100 Viterbo, Italy
Riccardo Marmo, Gastroenterology Unit, Ospedale di Polla, 84035 Polla, Salerno, Italy
Author contributions: Riccioni ME designed research; Urgesi R and Cianci R performed research; Rizzo G and Marmo R analyzed data; Riccioni ME, Cianci R, Urgesi R and D’Angelo L wrote the paper; Costamagna G revised the manuscript.
Correspondence to: Dr. Riccardo Urgesi, Gastroenterology and Digestive Endoscopy Unit, Ospedale Belcolle, Via Sammartinese, 01100 Viterbo, Italy. riurgesi@tin.it
Telephone: +39-6-30156580 Fax: +39-6-30156581
Received: February 15, 2013
Revised: April 11, 2013
Accepted: May 16, 2013
Published online: July 28, 2013
Revised: April 11, 2013
Accepted: May 16, 2013
Published online: July 28, 2013
Core Tip
Core tip: Although capsule endoscopy (CE) is widely used as a first-line diagnostic modality for obscure gastrointestinal bleeding after the execution of a work-out negative for gastrointestinal bleeding properly done by following the guidelines proposed by American Gas Association, the rebleeding rate after negative CE varies according to different studies. We tried to elucidate the outcomes after a negative CE for obscure gastrointestinal bleeding (OGIB) and to determine the risk factors associated with rebleeding. Based on the results of our study patients with OGIB and negative CE had a significantly lower rebleeding rate, and further invasive investigations can be deferred.