Published online Jul 14, 2013. doi: 10.3748/wjg.v19.i26.4166
Revised: April 16, 2013
Accepted: June 1, 2013
Published online: July 14, 2013
Core tip: Data on the effect of Helicobacter pylori (H. pylori) eradication on adult patients with iron-refractory or iron-dependent anaemia of previously unknown origin are scarce, and thus the frequency of H. pylori infection as the cause of anaemia in that setting is unknown. Resolution of iron-deficient anaemia (IDA) was observed in 32 out of the 84 H. pylori eradicated patients (38.1%). In all of them there was no relapse after a mean follow-up of 21 ± 2 mo. Thus, H. pylori infection was considered the aetiology of IDA in these cases. H. pylori infection as the aetiology of IDA was greater in men plus postmenopausal women than in premenopausal women (75.0% vs 23.3%, P < 0.0001).