Published online Jun 21, 2013. doi: 10.3748/wjg.v19.i23.3699
Revised: March 22, 2013
Accepted: April 27, 2013
Published online: June 21, 2013
Core tip: I believe the paper may be of particular interest to your readers because the reason is as follows. First, there has been rarity of case reports about esophageal metastasis from gastric cancer without any evidence of lymphatic involvement or direct spread from the primary lesion. Second, gastroesophageal reflux of cancer cells could be one of the possible metastatic pathways for metastasis of esophagus from an adenocarcinoma of the stomach, and this case proves the possibility of direct implantation of gastric adenocarcinoma cells refluxed on esophagus.