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World J Gastroenterol. Jun 7, 2013; 19(21): 3207-3216
Published online Jun 7, 2013. doi: 10.3748/wjg.v19.i21.3207
Published online Jun 7, 2013. doi: 10.3748/wjg.v19.i21.3207
Epidemiology, clinical-treatment patterns and outcome in 256 hepatocellular carcinoma cases
Luigi Fenoglio, Cristina Serraino, Elisabetta Castagna, Adele Cardellicchio, Fulvio Pomero, Department of Internal Medicine, Santa Croce Hospital, 12100 Cuneo, Piedmont, Italy
Maurizio Grosso, Department of Diagnostic Radiology, Santa Croce Hospital, 12100 Cuneo, Piedmont, Italy
Carlo Senore, AO Città della Salute e della Scienza, CPO Piemonte, 10123 Turin, Piedmont, Italy
Author contributions: Fenoglio L, Castagna E and Grosso M conceived and designed the study; Serraino C, Castagna E, Pomero F and Senore C acquired, analyzed and interpreted the data; Fenoglio L, Serraino C, Castagna E and Senore C drafted the manuscript; Serraino C, Castagna E and Cardellicchio A wrote the paper; Fenoglio L approved the final published version.
Correspondence to: Dr. Luigi Fenoglio, Department of Internal Medicine, Santa Croce Hospital, Via Michele Coppino 26, 12100 Cuneo, Piedmont, Italy. fenoglio.l@ospedale.cuneo.it
Telephone: +39-171-641308 Fax: +39-171-641306
Received: November 28, 2012
Revised: January 30, 2013
Accepted: March 15, 2013
Published online: June 7, 2013
Revised: January 30, 2013
Accepted: March 15, 2013
Published online: June 7, 2013
Core Tip
Core tip: Hepatocellular carcinoma (HCC) is the 5th most common cancer and the 3rd leading cause of cancer mortality worldwide. In recent decades, the incidence of HCC has risen in Europe and the United States. This study showed that, between 2000-2005 and 2005-2010, the number of hepatitis C virus-related HCC decreased, non-viral/non alcoholic etiologies increased and of surveillance programs were more frequently applied.