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World J Gastroenterol. Apr 7, 2013; 19(13): 2104-2109
Published online Apr 7, 2013. doi: 10.3748/wjg.v19.i13.2104
Published online Apr 7, 2013. doi: 10.3748/wjg.v19.i13.2104
Extended antimicrobial prophylaxis after gastric cancer surgery: A systematic review and meta-analysis
Chun-Dong Zhang, Yong-Ji Zeng, Zhen Li, Jing Chen, Hong-Wu Li, Jia-Kui Zhang, Dong-Qiu Dai, Department of Gastrointestinal Surgery, the Fourth Affiliated Hospital of China Medical University, Shenyang 110032, Liaoning Province, China
Author contributions: Zhang CD and Dai DQ conceived the study; Zhang CD and Zeng YJ collected data and performed data analysis; all authors designed the study and wrote the paper, read and approved the final manuscript for submission.
Correspondence to: Dong-Qiu Dai, Professor, Chief Physician, Department of Gastrointestinal Surgery and Cancer Center, the Fourth Affiliated Hospital of China Medical University, Shenyang 110032, Liaoning Province, China. daidq63@163.com
Telephone: +86-24-62043110 Fax: +86-24-62043110
Received: December 1, 2012
Revised: February 6, 2013
Accepted: March 6, 2013
Published online: April 7, 2013
Revised: February 6, 2013
Accepted: March 6, 2013
Published online: April 7, 2013
Core Tip
Core tip: We investigated the efficacy of extended antimicrobial prophylaxis (EAP) after gastrectomy through systematic review of literature and meta-analysis. We recommend that EAP should not be used routinely after gastrectomy until more high-quality randomized controlled trials are available.