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World J Gastroenterol. Apr 7, 2013; 19(13): 2097-2103
Published online Apr 7, 2013. doi: 10.3748/wjg.v19.i13.2097
Published online Apr 7, 2013. doi: 10.3748/wjg.v19.i13.2097
Chemotherapy and resection for gastric cancer with synchronous liver metastases
Lei Chen, Hui-Zhong Lin, Department of Surgery, Qingdao Municipal Hospital, Qingdao 266011, Shandong Province, China
Lei Chen, Shandong University School of Medicine, Jinan 250012, Shandong Province, China
Ming-Quan Song, Xiang-Jun Jiang, Department of Gastroenterology, Qingdao Municipal Hospital, Qingdao 266011, Shandong Province, China
Lin-Hua Hao, First Institute of Oceanography, State Oceanic Administration, Qingdao 266011, Shandong Province, China
Zi-Yu Li, Department of Surgery, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University School of Oncology, Beijing Cancer Hospital and Institute, Beijing 100142, China
Yu-Xin Chen, Department of Surgery, Qilu Hospital Affiliated to Shandong University School of Medicine, Jinan 250012, Shandong Province, China
Author contributions: Chen L, Song MQ and Lin HZ contributed equally to this work; Chen L, Song MQ and Jiang XJ designed the research; Chen L, Lin HZ, Li ZY and Chen YX performed the research; Hao LH analyzed the data; Chen L, Song MQ and Chen YX wrote the paper.
Correspondence to: Yu-Xin Chen, Professor, Department of Surgery, Qilu Hospital Affiliated to Shandong University School of Medicine, 107 Wenhuaxi Road, Jinan 250012, Shandong Province, China. yxchen@sdu.edu.cn
Telephone: +86-532-82789562 Fax: +86-532-82789561
Received: December 29, 2012
Revised: February 23, 2013
Accepted: March 6, 2013
Published online: April 7, 2013
Revised: February 23, 2013
Accepted: March 6, 2013
Published online: April 7, 2013
Core Tip
Core tip: We investigated the effect of surgery and chemotherapy for gastric cancer with multiple synchronous liver metastases (GCLM). Perioperative weekly docetaxel, cisplatin and 5-fluorouracil and S-1 and cisplatin achieved a good response, and combined with surgery, they could improve prognosis of GCLM.