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World J Gastroenterol. Nov 7, 2012; 18(41): 5925-5931
Published online Nov 7, 2012. doi: 10.3748/wjg.v18.i41.5925
Published online Nov 7, 2012. doi: 10.3748/wjg.v18.i41.5925
Effects of the viability of Lactobacillus rhamnosus GG on rotavirus infection in neonatal rats
Hanna Ventola, Liisa Lehtoranta, Riitta Korpela, Reetta Holma, Institute of Biomedicine, Pharmacology, University of Helsinki, FI-00014 Helsinki, Finland
Mari Madetoja, Toxis Ltd Oy, Lemminkäisenkatu 14-18 C, FI-20520 Turku, Finland
Marja-Leena Simonen-Tikka, Merja Roivainen, Intestinal Viruses Unit, National Institute for Health and Welfare, FI-00271 Helsinki, Finland
Leena Maunula, Department of Food Hygiene and Environmental Health, University of Helsinki, FI-00014 Helsinki, Finland
Author contributions: Holma R, Korpela R, and Madetoja M designed the study; Holma R supervised and organized the study; Ventola H and Lehtoranta L designed and carried out the animal experiments, subsequent molecular analyses, and drafted the manuscript; Madetoja M designed and carried out the animal experiments; Simonen-Tikka ML participated in the rotavirus-PCR analysis; Maunula L cultivated and provided the rotavirus strain, and participated in drafting the manuscript; Roivainen M participated in the study design, and helped to develop the rotavirus-PCR method; all authors read and approved the final manuscript.
Supported by Valio Ltd and the Finnish Funding Agency of Technology and Innovation; The Foundation for Nutrition Research has financially contributed to Liisa Lehtoranta’s doctoral studies
Correspondence to: Dr. Reetta Holma, Institute of Biomedicine, Pharmacology, University of Helsinki, PO Box 63, FI-00014 Helsinki, Finland. reetta.holma@helsinki.fi
Telephone: +358-9-19124366 Fax: +358-9-19125364
Received: January 13, 2011
Revised: February 28, 2012
Accepted: March 20, 2012
Published online: November 7, 2012
Revised: February 28, 2012
Accepted: March 20, 2012
Published online: November 7, 2012
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