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World J Gastroenterol. Apr 28, 2012; 18(16): 1875-1883
Published online Apr 28, 2012. doi: 10.3748/wjg.v18.i16.1875
Published online Apr 28, 2012. doi: 10.3748/wjg.v18.i16.1875
Probiotic metabolites from Bacillus coagulans GanedenBC30TM support maturation of antigen-presenting cells in vitro
Kathleen F Benson, Kimberlee A Redman, Steve G Carter, Gitte S Jensen, NIS Labs, 1437 Esplanade, Klamath Falls, OR 97601, United States
David Keller, Sean Farmer, Ganeden Biotech, 5915 Landerbrook Drive, Mayfield Heights, OH 44124, United States
John R Endres, AIBMR Life Sciences, 4117 S Meridian, Puyallup, WA 98373, United States
Author contributions: Jensen GS, Keller D, Farmer S, and Endres JR conceived the idea to test and compare the bioactivity of bacterial cell walls and metabolites; Jensen GS and Benson KF planned the procedure for generating the two test fractions; Jensen GS and Benson KF designed the study and coordinated the lab work and data analysis; Benson KF performed the production of the GBC30 fractions; Benson KF, Redman KA, and Carter SG performed the in vitro testing, analysis, and contributed to the writing of the manuscript; Benson KF did the statistical analysis; Benson KF, Jensen GS, Keller D, Farmer S and Endres JR finalized the manuscript writing.
Supported by A Research Sponsorship from Ganeden Biotech, Ohio, United States
Correspondence to: Kathleen F Benson, PhD, NIS Labs, 1437 Esplanade, Klamath Falls, OR 97601, United States. kathy@nislabs.com
Telephone: +1-541-8840112 Fax: +1-403-4415236
Received: July 30, 2011
Revised: December 20, 2011
Accepted: April 1, 2012
Published online: April 28, 2012
Revised: December 20, 2011
Accepted: April 1, 2012
Published online: April 28, 2012
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