Brief Article
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World J Gastroenterol. Dec 14, 2011; 17(46): 5089-5096
Published online Dec 14, 2011. doi: 10.3748/wjg.v17.i46.5089
Evaluation of latent links between irritable bowel syndrome and sleep quality
Massimo Bellini, Angelo Gemignani, Dario Gambaccini, Simona Toti, Danilo Menicucci, Cristina Stasi, Francesco Costa, Maria Gloria Mumolo, Angelo Ricchiuti, Remo Bedini, Nicola de Bortoli, Santino Marchi
Massimo Bellini, Dario Gambaccini, Cristina Stasi, Francesco Costa, Maria Gloria Mumolo, Angelo Ricchiuti, Nicola de Bortoli, Santino Marchi, Gastrointestinal Unit, Department of Gastroenterology, University of Pisa, 56100 Pisa, Italy
Angelo Gemignani, Danilo Menicucci, Remo Bedini, Institute of Clinical Physiology, National Research Council, 56100 Pisa, Italy
Angelo Gemignani, Danilo Menicucci, Remo Bedini, Extreme Centre, Scuola Superiore S Anna, 56100 Pisa, Italy
Angelo Gemignani, Department of Physiological Science, University of Pisa, 56100 Pisa, Italy
Simona Toti, Italian National Institute of Statistics, 00185 Rome, Italy
Author contributions: Bellini M contributed to patient enrollment, diagnosis of IBS, experimental design, and writing the manuscript; Gemignani A contributed to assessment of sleep disturbances, experimental design, and writing the manuscript; Gambaccini D contributed to patient enrollment, diagnosis of IBS, and writing the manuscript; Toti S and Menicucci D contributed to application of the IRT model and statistical analysis; Stasi C, Mumolo MG and de Bortoli N contributed to patient enrollment and diagnosis of IBS; Costa F performed lower digestive endoscopy in patients > 50 years old to exclude non-functional GI disorders; Ricchiuti A performed in all patients abdominal ultrasonography to exclude non-functional GI disorders; Bedini R contributed to statistical analysis and funded the study; Marchi S contributed to patient enrollment, diagnosis of IBS and funded the study.
Correspondence to: Dr. Massimo Bellini, Gastrointestinal Unit, Department of Gastroenterology, University of Pisa, Via Paradisa No. 2, 56100 Pisa, Italy. mbellini@med.unipi.it
Telephone: +39-50-997448 Fax: +39-50-997398
Received: January 31, 2011
Revised: March 28, 2011
Accepted: April 5, 2011
Published online: December 14, 2011
Core Tip