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World J Gastroenterol. Feb 7, 2010; 16(5): 618-624
Published online Feb 7, 2010. doi: 10.3748/wjg.v16.i5.618
Published online Feb 7, 2010. doi: 10.3748/wjg.v16.i5.618
Natural course of chronic hepatitis B is characterized by changing patterns of programmed death type-1 of CD8-positive T cells
Xue-Song Liang, Chen-Zhong Li, Mo-Bin Wan, Department of Infectious Diseases, Changhai Hospital, Second Military Medical University, Shanghai 200433, China
Ying Zhou, Department of Biochemistry and Molecular Biology, Second Military Medical University, Shanghai 200433, China
Author contributions: Liang XS and Zhou Y contributed equally to this work; Liang XS provided the vital reagents and analytical tools and wrote the manuscript; Zhou Y performed the majority of experiments; Li CZ took the charge of collecting all human materials; Wan MB designed the study and provided the financial support for this work.
Supported by Grants from the “Yucai” Research Program of Changhai Hospital
Correspondence to: Mo-Bin Wan, Professor, Department of Infectious Diseases, Changhai Hospital, Second Military Medical University, Shanghai 200433, China. mobinwan@yahoo.com.cn
Telephone: +86-21-81873504 Fax: +86-21-65518368
Received: September 3, 2009
Revised: December 2, 2009
Accepted: December 9, 2009
Published online: February 7, 2010
Revised: December 2, 2009
Accepted: December 9, 2009
Published online: February 7, 2010
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